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Chemistry Forums for Students => Analytical Chemistry Forum => Topic started by: pollypui on April 16, 2013, 01:25:43 PM

Title: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 16, 2013, 01:25:43 PM
anyone know the pKa of pyroglutamaic acid with reference~
thank you very much!!
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: Arkcon on April 16, 2013, 01:45:36 PM
Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 16, 2013, 01:53:36 PM
Plenty of people do:  http://lmgtfy.com/?q=pyroglutamaic+acid  You could find it at the Wikipedia article, or on the vendor MSDS, for example, Sigma-Aldrich


i try it before many time, but i cant found it out:'( :'( :'(
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: Arkcon on April 16, 2013, 03:13:08 PM
The first and third results in my Google search, which I linked to above, contained the information you need.
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 16, 2013, 11:50:52 PM
The first and third results in my Google search, which I linked to above, contained the information you need.

The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: AWK on April 17, 2013, 01:30:50 AM
The first pK
Quote
a
(-1.76) is Wikipedia is suspicious
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 17, 2013, 01:48:11 AM
The first pK
Quote
a
(-1.76) is Wikipedia is suspicious

yes.. so i need the pka with the reference, and i find many hand book.
and none of book have the pKa of pyroglutamaic acid ??? ???
anyone can help me ><
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: billnotgatez on April 17, 2013, 03:49:52 AM
Is the information on
http://www.hmdb.ca/metabolites/hmdb00267
relevant

that was the 7th GOOGLE item
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: Arkcon on April 17, 2013, 06:31:19 AM
The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: AWK on April 17, 2013, 08:11:38 AM
http://link.springer.com/article/10.1007%2Fs10953-005-5121-x?LI=true

Journal of Solution Chemistry
July 2005, Volume 34, Issue 7, pp 853-867

Electrical Conductance and Volumetric Studies in Aqueous Solutions of DL-Pyroglutamic Acid
Zoya Orekhova, Yonit Sambira, Emanuel Manzurola, Alexander Apelblat
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 17, 2013, 09:54:00 AM
The first one is wiki, the reference article that i cant find the free version. :-\
this is my final year project, so i must find it out prove my data right~
and the pka of pyroglutamic acid do not show in the sigma MSDS.... :(

Sorry.  But this is silly.  If wikipedia isn't a useful reference for you, how is a forum posting acceptable?  Will your bibliography or footnote list: personal communication, The Cheimestrie Geeks forums, user: Pee-Kay-Hay God ?  That's not a good reference either.  You will simply have to search the library for a decent source, or buy one.

sorry to my impolite..
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: AWK on April 17, 2013, 09:59:16 AM
In my reference pKa1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: Corribus on April 17, 2013, 10:47:30 AM
If you're having so much trouble finding this value, why not just measure it yourself?
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: pollypui on April 17, 2013, 12:31:45 PM
In my reference pKa1 of pyroglutamic acid was measured. Moreover, references to previous measurements are given.

thank you very much!! :)
is that mean PCA only have one pka?
Title: Re: anyone know the pKa of pyroglutamaic acid
Post by: AWK on April 18, 2013, 03:05:00 AM
Just look at structural formula