Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: zsinger on November 19, 2013, 08:09:47 PM
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All,
About to perform a wacker oxidation, and I decided to use P-Benzoquinone instead of CuCl2 as my oxidant this time . I have only performed this reaction once in the lab, as it is almost always scaled up. I prefer the Formic Acid/H2O2 with 5M H2SO4 workup to get the desired ketone (stick with what you know!), but I wanted to practice this method, as oxygen is cheap, and P-Benzo is not all that expensive! Thanks for any/all help. The Rxn. hopefully should proceed as follows (balanced): 2 Ethylene, add PdCl2, Add p-benzoquinone-->2 CH3COH.
-Zack
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What are you attempting to oxidise? by the looks of your post you are attempting to make acetaldehyde from ethene.
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I am trying this on the terminal end of Eugenol to get the desired ketone. I just posted the acetaldehyde expression to explain my additions, etc. Thanks
-Z
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Eugenol huh. Then what, safrole??
I am suspicious about this post.
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I am trying this on the terminal end of Eugenol to get the desired ketone. I just posted the acetaldehyde expression to explain my additions, etc. Thanks
-Z
Wacker oxidation does not give the ring substituted 1-arylpropan-2-one with eugenol.
See http://www.sciencedirect.com/science/article/pii/S0040403901803026 for details.
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Anyways, ill figure it out I guess.
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Retracted statement.
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Also, If you know of a way to go from Eugenol to Safrole without adding HI and disrupting that double bond, you would be a rich man (or woman).
I am not familiar with US law but certainly in many parts of the world if you succeeded in synthesising safrole by any route you would be committing a very serious offence.
Many roads lead to Rome, in this case fortune is not found there.
Probably something to avoid discussing on this forum.