Chemical Forums
Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: organicdave on December 05, 2013, 05:45:28 PM
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So a natural product I am working on in my lab has an extremity that is an a terminal butene. My goal is to oxidize the alkene selectively to form a ketone which will in turn make my molecule more water soluble. I've seen that palladium (II) chloride is an oxidation catalyst selective to ketone formation. The reaction is called a Wacker Oxidation. My issue rises with the cost or equipment that most of the literature I find calls for with the oxygen source. I've read experimentals that use both molecular O2 and parabenzoquinone. I'm looking for a substitute for the p-benzoquinone that I hopefully already have in stock. So far the only one's I can think of are trioxane or dioxane and I believe these would also call for a follow-up reaction to shape my desired molecule. Maybe KBrO3? I'm new to oxidation and was wondering if anyone in this forum could help. Thanks!