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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: organosurf on March 04, 2014, 11:04:43 AM

Title: Zinc / HCl reduction
Post by: organosurf on March 04, 2014, 11:04:43 AM

Does anyone know the exact reaction conditions ( proportion of reactants, conc of acid, eq of Zn, etc ) and especially yields for the above to reduce an aliphatic primary halide ( R-Cl ) to its alkane ?
Though there is a lot of mention of this reaction on the web, there are absolutely no detailed reaction conditions given anywhere. Have checked far and wide, just got one ref that gave a measly yield of 12%.
How about using Aluminum with acid for such reductions ? There is no mention of this anywhere...

Title: Re: Zinc / HCl reduction
Post by: AlphaScent on March 04, 2014, 01:43:17 PM

Do you have access to journals?

http://www.sciencedirect.com/science/article/pii/S0040403900781858

I am sure they talk in detail about the utility of the reaction.

Title: Re: Zinc / HCl reduction
Post by: organosurf on March 10, 2014, 05:15:20 AM

Thanks alphascent. Most examples just say Zn / HCl or Acetic. Dont mention the reaction conditions ie. temperature and time, as an approximate guide. Of course, each set of reactants have their specific conditions.