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Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: kamiyu on June 28, 2014, 03:04:08 PM

Title: About nucleophilic aromatic substitution reaction
Post by: kamiyu on June 28, 2014, 03:04:08 PM

You know, you can add some nucleophile such as OH- ion to replace Cl or F atoms on electron deficient ring (SNAr).

I am wondering if it is possible to replace the fluorine with hydrogen atom, i.e. using sodium hydride?

Any experience or knowledge about how to replace the F with H???