Chemical Forums
Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: orgo814 on October 20, 2014, 08:22:12 PM
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"In addition to lactose, how many other heterodisaccharides can D-galactose and D-glucose form?"
The answer is 39 in addition to lactose. But, I'm struggling to find a logical way to solve this. I look at number of chiral stereocenters to see stereoisomers but that did not help. I looked at beta and alpha combinations but that also falls way short of 39. Please help
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I get 20 (including lactose) considering pyranose forms only.
If I consider two disaccharides different if they vary only by the configuration at the non-glycosidic anomeric centre, which would not be correct to do, I get 36. If I forgot to remove degenerate pairs from that list, which would not be correct to do, I would have 40 (which matches the answer, that may be coincidence though).
If I consider combinations of pyranose and furanose forms I get 80.
So I'm stumped as well... I can only get 40 by making two mistakes.
If it doesn't get solved on here with someone else's help, please post the solution when you have it.
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My professor confirmed it was a book mistake. Thanks anyways though... I was there for a half hour trying to solve it!
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@butlerw2 Out of curiosity
What should have the answer been according to your professor?
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I was also interested in that question. After some thought, I agree with Dan that the number is probably 20, as long as we restrict ourselves to pyranoses.
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He said about half that number so probably around 20