Chemical Forums

Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: Mpatas on January 27, 2015, 01:39:57 PM

Title: Amine oxidation to nitro group
Post by: Mpatas on January 27, 2015, 01:39:57 PM

I tried this reaction today by using a mixture of sulfuric acid/Hydrogen peroxide but i was very confuse during the work up of the reaction. Some papers suggest to bacify the solution first and then extract it but i also found procedures that they just extract the reaction mixture. Is that possible? Can i get my product in the organic phase while it is acidic?

Title: Re: Amine oxidation to nitro group
Post by: kriggy on January 27, 2015, 05:06:56 PM

Well try it. Ithink acidic conditions hels to keep the amine in aquaeous phase but it might depend on the specific molecule

Title: Re: Amine oxidation to nitro group
Post by: Dan on January 28, 2015, 05:25:58 AM

Quote from: Mpatas on January 27, 2015, 01:39:57 PM

Can i get my product in the organic phase while it is acidic?

It depends. Will the product be charge neutral under these conditions?