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Chemistry Forums for Students => Organic Chemistry Forum => Organic Chemistry Forum for Graduate Students and Professionals => Topic started by: phth on June 19, 2016, 08:28:25 PM

Title: MOM chloride
Post by: phth on June 19, 2016, 08:28:25 PM

Has anyone handled this chemical?  Storage conditions? Is vacuum distillation a bad idea?

Title: Re: MOM chloride
Post by: Guitarmaniac86 on June 20, 2016, 01:38:12 AM

Store it at 2 - 8 degrees C (so in the fridge).

When I use it, I place it in a clamp stand so it cant fall over in the fumehood. I use needles to take it up and add it to my flask dropwise.

Any needles, syringes, glassware etc, is left in NaOH solution overnight.

I wouldnt use vacuum distillation only because its nasty carcinogenic stuff. After work up, I will use a rotary evaporator but I would never distill MOM-Cl before use.

Title: Re: MOM chloride
Post by: TheUnassuming on June 20, 2016, 03:18:05 PM

As long as the bottle is really old/misused and your reaction isn't extremely sensitive, you shouldn't need to repurify MOMCl.   

Its a membrane permeable alkylating agent, so keep it in the fume hood, don't sniff it, wear gloves, and you will be fine.

Title: Re: MOM chloride
Post by: rolnor on August 07, 2016, 06:36:10 AM

I beleive it is listed as carcinogenic but MOMBr is not?

Title: Re: MOM chloride
Post by: rolnor on August 22, 2016, 08:19:49 AM

Also, is not the carcinogenic properties coming from the prescense och some bis-chloromethylether wich is formed from formaldehyde and hydrogen chloride in the synthesis?