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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: Frankenstein_2016 on July 14, 2016, 10:48:40 AM

Title: Ph problems??
Post by: Frankenstein_2016 on July 14, 2016, 10:48:40 AM

Converting Benzocaine>>>>>>benzocaine hydrochloride


Hi can anybody help me solve this problem??
Benzocaine>>>>>benzocaine Hydrochloride

I am doing an acid base extraction using benzocaine base
Using the following method
Dissolving benzocaine base in acetone
Also Using 36% hcl and methanol
I am getting a final ph of around 2.5
How do I raise the ph and also I think this is because the acid is getting trapped inside the crystals
Anybody help?

Title: Re: Ph problems??
Post by: AWK on July 14, 2016, 10:50:57 AM

Hint - neutralization of acid. For esters in organic solvents very often K₃CO₃ is used.

[something gone wrong with subscripts]

Title: Re: Ph problems??
Post by: phth on July 15, 2016, 02:14:00 AM

Are you sure that is what an extraction is called?  What you have stated is you will protonate a neautral molecule in partially solvating conditions.  An extraction involves using a system that can be partitioned.  The only thing possible is hexane, and the partition coef will still be s#*$ if you try