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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: guzmanov on May 27, 2017, 12:43:41 PM

Title: Can anybody help me doing this exercise?
Post by: guzmanov on May 27, 2017, 12:43:41 PM

I know is a Claisen condensation but i'm not sure how to do the mechanism nor what happens after you add H2O. :(

Thank you in advance! :D

Title: Re: Can anybody help me doing this exercise?
Post by: sjb on May 27, 2017, 01:20:39 PM

What happens if you just try a Claisen addition (looking at the number of oxygens)?

Title: Re: Can anybody help me doing this exercise?
Post by: kriggy on May 27, 2017, 02:06:48 PM

Quote from: guzmanov on May 27, 2017, 12:43:41 PM

I know is a Claisen condensation ...

its not Claisen however

Title: Re: Can anybody help me doing this exercise?
Post by: spirochete on June 05, 2017, 02:53:12 PM

First few steps look like aldol or Knoevenagal (sp?). Second set of steps look like key steps from malonic ester/acetoacetic ester synthesis.

-H2O means "loss of water" by the way. It does not mean "add water". In case that was a point of confusion.