Chemical Forums

Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: E_Euler on June 07, 2018, 09:12:58 AM

Title: Lipid Metabolism disorder
Post by: E_Euler on June 07, 2018, 09:12:58 AM

Hello guys, is the formation of ketone bodies a lipid metabolism disorder??
I know they form in people with diabetes ( carbohydrate metabolism disorder). but can we consider it also as a lipid metabolism disorder??

Title: Re: Lipid Metabolism disorder
Post by: Babcock_Hall on June 14, 2018, 09:27:54 AM

Formation of ketone bodies in general is a normal during a long fast or starvation.  I would call this ketosis.  Ketone bodies are water-soluble derivatives of fatty acids that were stored as triacylglycerols.  Ketoacidosis, for example, results from type I diabetes, and is a state in which ketone bodies are produced despite a person's eating a normal diet.  The acidosis means that the pH of blood is low, sometimes dangerously low.  Ketoacidosis can sometimes be seen in type II diabetes, but my understanding is that it is less common.  I would not classify diabetes as solely a disorder of carbohydrate metabolism, because insulin affects many metabolic pathways.