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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: kemist on November 21, 2018, 11:52:29 AM

Title: Looking for helo to reduce nitro and alkene in this stilbene.
Post by: kemist on November 21, 2018, 11:52:29 AM

Hello everyone,
Looking for helo to reduce nitro and alkene in this stilbene.
What one pot reaction (or two steps) condition you suggest (Other the Zn/HCl followed by NH4Cl).
Use of Pd.C remove the Cl. So these two condition can not be used.
Thanks

Title: Re: Looking for helo to reduce nitro and alkene in this stilbene.
Post by: rolnor on November 22, 2018, 04:49:34 AM

NaBH4/Pd-C in methanol, if you do this carefull I dont think you will remove the Cl. You will need large excess NaBH4 and add it in small portions.

Title: Re: Looking for helo to reduce nitro and alkene in this stilbene.
Post by: kriggy on November 22, 2018, 07:40:28 AM

You can try different catalyst as well. Colleagues had good experience with PtO2 or Pt/C. Or poisoning the palladium catalyst: Org. Lett., 2006, 8, 3279-3281.