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Chemistry Forums for Students => Organic Chemistry Forum => Topic started by: mazing on January 19, 2019, 03:17:40 PM

Title: How to determine most soluble compound in different solvents?
Post by: mazing on January 19, 2019, 03:17:40 PM

If i have a set of different polar organic compounds and different polar (protic and aprotic) solvents, how can i determine which compound will be the most soluble in each of the solvents? This without using any sort of tools such as a solubility predictor. What difference between the compounds should I note to determine the relative solubility of each?

Title: Re: How to determine most soluble compound in different solvents?
Post by: rolnor on January 21, 2019, 01:22:17 PM

Do you have any ideas? I think hydrogen bonding ability, dipolmoment and large lipophilic parts in the molecule are important. Can you maybe post the structures here?

Title: Re: How to determine most soluble compound in different solvents?
Post by: wildfyr on January 21, 2019, 01:29:50 PM

Also, remember that sometimes things are truly miscible, not just soluble.