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Specialty Chemistry Forums => Biochemistry and Chemical Biology Forum => Topic started by: akuhl101 on January 25, 2019, 07:39:20 PM

Title: Alpha-Methyl-L-tyrosine vs Alpha-methyl-P-tyrosine - same or different
Post by: akuhl101 on January 25, 2019, 07:39:20 PM
Hi all,

Been struggling with this one and hoping an expert can assist me, appreciate any help I can get!

Alpha-Methyl-L-tyrosine vs Alpha-methyl-P-tyrosine. they have the same chemical formula but different CAS registry numbers: does that mean they are isomers and not identical molecules?

Alpha-methyl-p-tyrosine has CAS # 658-48-0 https://en.wikipedia.org/wiki/AMPT
α-Methyl-L-tyrosine has CAS # 672-87-7 https://www.sigmaaldrich.com/catalog/search?term=672-87-7&interface=CAS%20No.&N=0&mode=partialmax&lang=en&region=US&focus=product

Thank you again!
Andrew
Title: Re: Alpha-Methyl-L-tyrosine vs Alpha-methyl-P-tyrosine - same or different
Post by: AWK on January 26, 2019, 04:57:06 AM
AMPT is a racemate
cf. https://wiki2.org/en/Metirosine 
Title: Re: Alpha-Methyl-L-tyrosine vs Alpha-methyl-P-tyrosine - same or different
Post by: sjb on January 26, 2019, 05:05:13 AM
Based on the text of the wiki article for AMPT at this time alone (https://en.wikipedia.org/w/index.php?title=AMPT&oldid=765832635 ) I think AMPT is the racemate, and "AMLT" is a specific enantiomer. But two caveats -