So i'm looking into deformulations of paints and i've noticed that GPC might be a good way to start, considering that i wouldn't have to separate each component of the formulation in order to do quantitative analysis (i would use FT IR if necessary for compound identification then proceed with the tests according to the compound).
Considering that paints formulations are more or less the same (for example nitrocellulose is a very common compound) i was thinking on making a calibration curve for this compound in specific, plotting Peak Area x Nitrocellulose concentration. However, on my research i did not find if the molecular weight affects this peak area or is it only dependent of the concentration of the sample (I'm dont have much knowledge about GPC), because there are NCs of varied molecular weight. I've found a paper but it didn't mention if the molecular weight varies to the detector response or if is it only the sample concentration.
So, is this quantitative method viable? Separating each compound individually and proceeding to techniques like FT IR/GC/HPLC would be better? Also, im looking for the maximum precision in the quantitative analysis.