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Topic: Synthesis of ondansetron  (Read 1021 times)

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Offline gabsalks

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Synthesis of ondansetron
« on: June 30, 2019, 11:43:10 PM »
Hi guys,

I'm having serious trouble with this homework. The first part I've already solved, it's the second one (the one marked with the "?*") that got me stuck. I'm not sure what to add to the carbonyl group that will facilitate the next reactions. Can someone give me a light?

Thanks!

Offline rolnor

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Re: Synthesis of ondansetron
« Reply #1 on: July 01, 2019, 04:25:09 AM »
In the first step, will not the aldehyde react with the amino-group?

Offline gabsalks

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Re: Synthesis of ondansetron
« Reply #2 on: July 01, 2019, 10:28:24 AM »
Hi rolnor, thanks for the reply.
I think the way it's written may be a little confusing. The reactions have to happen in this order.

Offline Babcock_Hall

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Re: Synthesis of ondansetron
« Reply #3 on: July 01, 2019, 02:39:02 PM »
If you work backward from your product, something may occur to you.

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