Hi every one,
I am confused that when we compare Stille coupling and Suzuki coupling (toxicity is exception), which one is better (reactivity, regioselectivity, reaction yield,...)?
I know that the coupling reactions are complicated with many different reactants, but when I check literature for synthesizing conjugated system, Stille coupling is more preferable. Ex: to synthesize 5,6-dinitro-4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadiazole, they almost only use Stille coupling between 4,7-dibromo-5,6-dinitrobenzo[c][1,2,5]thiadiazole and 2-(Tributylstannyl)thiophene.
Could you please tell me which one is better and what is the reason?