I work in R&D. It will depend on your company culture, manager, holiday allowance, pay etc.
I worked in England for 2 years and now in Canada. Overall in England you are paid less than Canada, which can add to stress, but you will have a more generous holiday allowance.
Now I'm in Canada and technically our holiday allowance is unlimited, but generally take over 3 weeks and you will need to have a good reason for taking more time off.
As I'm more senior now there is more work to do, which can add to stress, but I still work less than 40 hours per week, and the work is more interesting due to being in charge of my own projects.
In England many companies will have a 36-38 hour week as standard.
Overall I would highly recommend industry over academia, which is known for very low pay and much longer hours. For example, I just finished my PhD last year, and I earn double the average postdoc in Canada. It brings a lot of stress down when you're able to buy a house and provide food for your kids, along with job security.