February 28, 2020, 04:21:24 PM
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Topic: Synthesis of N-Acyl-N,O-alcohol  (Read 148 times)

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Offline Bertrand

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Synthesis of N-Acyl-N,O-alcohol
« on: January 07, 2020, 06:28:38 AM »
 :) Hello everyone

I have some problems with making a connection in order to reach the final product of my synthesis.

I want to connect and amide an aldehyde thought a nucleophilic addition in order to get an N, O-alcohol product (Hemiaminal).

could you please give some advice? I have been trying to make that connection for a month using several papers but none of them lead me to the product.

Thank you very much in advance for your propositions

Offline sjb

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Re: Synthesis of N-Acyl-N,O-alcohol
« Reply #1 on: January 07, 2020, 08:46:46 AM »
Please don't cross-post. Locked here

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