A physician wishes to prepare a buffer solution at pH = 3.82 that if ciently
resists changes in pH yet contains only small concentrations of the buffering
agents. Determine which one of the following weak acids, together with its
sodium salt, would probably be best to use: m-chlorobenzoic acid, Ka = 1.04e-4
; p-chlorocinnamic acid Ka = 3.89e-5 ; 2,5-dihydroxybenzoic acid, Ka = 1.08e-3
; or acetoacetic acid, Ka = 2.62e-4. Explain.
do we use Henderson-Hasselbalch?