Chemistry Forums for Students > Organic Chemistry Forum
How does the liver does this mechanism wise?
sharbeldam:
What is the mechanism of this reaction ( metabolism of a drug )
Thanks for help
I would have put my try but I honestly have no idea how the liver does this for the drug. it converted a single bond to enol.
Babcock_Hall:
As you know, it is up to you to share you thoughts before we can help you. I will try to give you a start. How would you classify the reaction that you have drawn (meaning is it an isomerization, reduction, etc.)? What liver enzymes do you know that are involved with xenobiotics?
AWK:
It is probably enzymatic oxidation by one of from cytochrome P450 family.
sharbeldam:
I might be of a beginner level, I know it's enzymatic but the oxidation that I know in chemical synthesis do not usually transform single bond to enol, is there a mechanism ( a specific reaction that we learn in O-chem ) that explains how an enzyme does this?
AWK:
Enzymic reactions are always stepwise.
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