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Topic: Robinson annulation product  (Read 494 times)

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Offline Allendo

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Robinson annulation product
« on: May 15, 2020, 01:53:23 AM »
Hi Team
Please find a reaction I draw in the attachment. It is a classic example for Robinson annulation.
The Michael part is straightforward.

In the attachment, I also included 2 possible aldol products.
A is commonly regarded as the correct product. I also agree with it.
B is my personal creation. It also form 2 six membered rings

My suspicion that the last product from B is not formed is due to the severe steric hinderance.  But on the other hand, the conj double bond have to be on the same plane and the left part of the 3 carbon can form a chair the 3D structure I imagined the last.

Any help is appreciated

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