September 27, 2022, 12:24:52 AM
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Topic: How would you make Metampicillin Sodium from Metampicillin?  (Read 1146 times)

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Offline rethroo

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I am trying to get salt form of metampicillin but don't know how. I think it is metampicillin soidum but how can I get that? How is the reaction happen?

 You can see metampicillin and metampicillin sodium in the attachment.

Offline chenbeier

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #1 on: June 14, 2020, 05:05:07 AM »
Do you know acid base neutralisation?

Offline Babcock_Hall

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #2 on: June 14, 2020, 10:34:27 AM »
What do you wish to do with the sodium metampicillin?

Offline rethroo

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #3 on: June 14, 2020, 10:41:25 AM »
What do you wish to do with the sodium metampicillin?
nothing, it is my homework.

Offline rethroo

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #4 on: June 14, 2020, 10:42:07 AM »
Do you know acid base neutralisation?
I actually made it like that but it seemed too easy so I wasn't sure.

Offline AWK

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #5 on: June 14, 2020, 12:43:10 PM »
Stoichiometry of acid and base reactions is usually very simple.
In practice, the reaction direction is different. It is from ampicillin salt that, in reaction with formaldehyde, metampicillin sodium is obtained.
AWK

Offline Babcock_Hall

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Re: How would you make Metampicillin Sodium from Metampicillin?
« Reply #6 on: June 14, 2020, 01:55:05 PM »
If one prepares a stock solution of ampicillin for bacterial work, one should keep careful control of pH.  You might give some thought as to how and why.

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