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Topic: GOC question  (Read 1066 times)

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Offline Gameofketones

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GOC question
« on: August 13, 2020, 04:07:42 AM »
Am I correct so far?

Offline rolnor

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Re: GOC question
« Reply #1 on: August 13, 2020, 09:11:26 AM »
Its really not very good to alkylate alkyllithium compounds with alkyl iodides, better make cuprate. Its possible it works but very slow. Also its likely you get halogen-metal exchange rather than substitution.
« Last Edit: August 13, 2020, 11:23:06 AM by rolnor »

Offline Babcock_Hall

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Re: GOC question
« Reply #2 on: August 13, 2020, 12:49:31 PM »
@OP, What sort of reaction do you intend for A to B?

Offline hollytara

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Re: GOC question
« Reply #3 on: August 14, 2020, 11:10:15 AM »
A to B....  has an alkene and a diene..  Did they teach you Diels-Alder?

Offline Gameofketones

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Re: GOC question
« Reply #4 on: August 14, 2020, 11:12:37 AM »
Yes isn't what I did diels Alder from A to B?

Offline Babcock_Hall

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Re: GOC question
« Reply #5 on: August 14, 2020, 02:33:38 PM »
@OP, What is the product of a standard Diels-Alder reaction?

Offline rolnor

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Re: GOC question
« Reply #6 on: August 14, 2020, 04:00:48 PM »
The alkene is not a dienophile, but still give DA?

Offline hollytara

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Re: GOC question
« Reply #7 on: August 14, 2020, 11:15:13 PM »
Rolnor - you CAN force 1,3-butadiene and ethene to do a Diels-Alder reaction at high pressure.  This is a paper synthesis - being intra molecular is a little like higher pressure!  I don't see what else an alkene and diene will do with just heat.

Offline Gameofketones

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Re: GOC question
« Reply #8 on: August 15, 2020, 05:59:02 AM »
These questions don't concern with the actual practicability of the reaction. These are just practice questions.

Offline AWK

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Re: GOC question
« Reply #9 on: August 15, 2020, 06:03:07 AM »
Then do an intramolecular Diels-Alder reaction correctly.
AWK

Offline Gameofketones

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Re: GOC question
« Reply #10 on: August 15, 2020, 06:44:56 AM »
Yeah, my bad..I was going for Diels Alder but messed it up

Offline rolnor

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Re: GOC question
« Reply #11 on: August 15, 2020, 08:51:16 AM »
OK, I understand.

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