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Topic: Grignard reagent  (Read 935 times)

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Offline Gameofketones

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Grignard reagent
« on: August 10, 2020, 04:40:53 AM »
Confused as to where the grignard reagent will attack..is it wat the double bond..or at the carbonyl carbon.. I've given the probable products..I think it will be at the double bond since carbonyl carbon is sterically hindered.

Offline AWK

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Re: Grignard reagent
« Reply #1 on: August 10, 2020, 05:11:07 AM »
Why do you think dibenzosuberone reacts abnormally with Grignard's reagent? I don't see any hindrance to the carbonyl group. An analogous method was used in the synthesis of loratidine.
AWK

Offline Gameofketones

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Re: Grignard reagent
« Reply #2 on: August 10, 2020, 05:22:13 AM »
Okay..I saw the double bond and was confused..

Offline Psychotic80

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Re: Grignard reagent
« Reply #3 on: August 17, 2020, 12:03:22 AM »
Okay..I saw the double bond and was confused..

Grignard add 1,2. Cupurates add 1,4.

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