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Topic: Lability of Lithium Bis(TMS) amide in THF  (Read 1101 times)

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Online Babcock_Hall

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Lability of Lithium Bis(TMS) amide in THF
« on: September 24, 2020, 12:22:59 PM »
I have some sure-seal bottles of this reagent that are two years old but have never been opened.  Could there be a reaction with THF over time?  Is the reagent likely to still be good?  Thank you.

Offline rolnor

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Re: Lability of Lithium Bis(TMS) amide in THF
« Reply #1 on: September 24, 2020, 04:03:45 PM »
I think it could be, BuLi certainly reacts fast with THF at roomtemp.
Can you test the reagent, if you have a indicator somehow? If you make a anion of triphenylmethane, this should be yellow and then titrate it with an acid to see how much is consumed until the color dissapear? Acetic acid would be OK?

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