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ADP hydrolysis to AMP yields the same E as less stable ATP to ADP, why?
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Qwerius_1:
I was learning some biochem. and I found out that ADP is more stable that ATP because of intramolecular repulsion of negative charges and because of resonance of ADP. I then thought that because of this, hydrolysis of ADP to AMP has to yield less energy that that of ATP, but found out that the ∆G is the same. How is this possible??
Babcock_Hall:
Are you familiar with the terminology of phosphoanhydride bond? Are you familiar with the term high-energy bond?
Babcock_Hall:
A high-energy bond is a bond for which the hydrolysis reaction has ΔG°' less than -25 kJ/mol. Are same factors which make the β,γ bond in ATP a high energy bond also a factor in the α,β bond in ADP?
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