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Topic: Acetic acid and GC analysis  (Read 21820 times)

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Offline mir

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Acetic acid and GC analysis
« on: September 27, 2006, 01:45:39 PM »
I have 0.08 mg/mL acetic acid in a sample with Ethyl acetate as a solvent.
I am not worried about fronting and tailing - The only thing I am worry about is...

- will I destroy the GC column if I inject so much Acetic acid?
No single thing abides, but all things flow.
Fragment to fragment clings, and thus they grow
Until we know and name them.
Then by degrees they change and are no more
The things we know.
- Titus Lucretius Carus

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Offline chiralic

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Re: Acetic acid and GC analysis
« Reply #1 on: September 29, 2006, 12:32:20 AM »
Hello mir:

Could you tell me what kind of column and detector are you using? Did you try use derivatisation?

I know that you said that you don't worried with fronting or tailing in your peaks but I would like to say this:

The direct analysis of low-molecular-mass carboxylic acids by gas chromatography (GC) is difficult because of the poor GC separation and detectability of these compounds. Their hydrophilic nature it
is difficult and cause analyte poor reproducibility. You can improved you separation by chemical derivatisation.

The derivatives (in most cases esters) display much better GC behaviour and their detection is more sensitive than that of the parent compounds. Separation of the acids from the sample matrix prior to derivatisation is therefore necessary.

Please I recommend you check out this references:

Vaidyanath Mahadevan, Lauren Stenroos.
Quantitative analysis of volatile fatty acids in aqueous solution by gas chromatography
Anal. Chem.; 1967; 39(13); 1652-1654.

R.J. Wells, Recent advances in non-silylation derivatization techniques for gas chromatography
J. Chromatogr. A 843 (1999) 1-18

A. Vairamurthy, K. Mopper,
Determination of low-molecular-weight carboxylic acids in aqueous samples by gas chromatography
and nitrogen-selective detection of 2-nitrophenylhydrazides
Anal. Chim. Acta 237 (1990) 215.

My best regards

Chiralic

Offline mir

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Re: Acetic acid and GC analysis
« Reply #2 on: September 29, 2006, 04:21:14 AM »
We are using an unpolar C18 column.

I am not going to analyze the acetic acid concentration. Acetic acid is the solvent in my reactionmixture. But I am perhaps going to dilute a sample in ethyl acetate.

I talked to the GC engineer. He said that Acetic acid do not affect the column. But may make so harsh condition in the FID-detector, in high concentration, that it will corrode.
No single thing abides, but all things flow.
Fragment to fragment clings, and thus they grow
Until we know and name them.
Then by degrees they change and are no more
The things we know.
- Titus Lucretius Carus

http://www.ife.no

Offline mir

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Re: Acetic acid and GC analysis
« Reply #3 on: November 14, 2006, 06:30:37 AM »
Is there any comments to what the GC-engineer told me?
No single thing abides, but all things flow.
Fragment to fragment clings, and thus they grow
Until we know and name them.
Then by degrees they change and are no more
The things we know.
- Titus Lucretius Carus

http://www.ife.no

Offline Sunit

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Re: Acetic acid and GC analysis
« Reply #4 on: September 01, 2009, 04:07:24 PM »
Hi
I am doing research on hydrogen production by steam reforming of acetic acid over a noble-metal catalyst.
I amnot understanding which type of GC-Column ,I have to use for acetic acid detection???
can someone guide me also that what should be the material of construction of reactor vessel which can work properly for acetic acid acround 500-700 degree C temperature range???


Sunit

Offline Don Shelly

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Re: Acetic acid and GC analysis
« Reply #5 on: September 10, 2009, 02:48:12 PM »
Add magnesium sulfate anhydrous to your extract.  Shake and filter.  Acetic acid will interfere with your chromatography.

Don

Offline AcOH

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Re: Acetic acid and GC analysis
« Reply #6 on: March 19, 2014, 05:57:19 AM »
Hello Sunit,

did you get an answer for your question about acetic acid detection in GC? i am also working in SR of acetic acid and i have to face the same problem.

Thank you,

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