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Topic: Determine pKa  (Read 1193 times)

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Offline rolnor

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Determine pKa
« on: October 08, 2020, 03:30:17 PM »
How does one determine pKa of a amineoxide under anhydrous conditions? I really dont have any clue about this, I have searched in the literature but cant find any relevant answer.
I did a new search, you can do it spectrophotometric in DMSO;
https://pubs.acs.org/doi/pdf/10.1021/ja00857a010

I am not sure that you can do it with such a strong acid as a protonated amineoxide though?
« Last Edit: October 08, 2020, 03:54:59 PM by rolnor »

Offline phth

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Re: Determine pKa
« Reply #1 on: October 10, 2020, 03:39:34 PM »
Should be fine. I would read about metal hydricities because I think you can find the answer to stability concerns in the literature. A review article that I quickly googled: Thermodynamic Hydricity of Transition Metal Hydrides https://doi.org/10.1021/acs.chemrev.6b00168 

Offline rolnor

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Re: Determine pKa
« Reply #2 on: October 11, 2020, 04:12:13 PM »
I dont understand your answer at all, I am talking about amineoxides?

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