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Topic: Major product of 2-iodopropane + sodium ethoxide  (Read 3056 times)

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Offline Meter

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Re: Major product of 2-iodopropane + sodium ethoxide
« Reply #15 on: November 25, 2020, 05:58:02 PM »
You have a secondary alkyl iodide, not a tertiary.  The reading I have done indicates that if one uses a polar, aprotic solvent, one might tilt things toward the SN2.  Can you give an example of such a solvent?
Yes, I'm aware that it's not tertiary. It was just a point where SN2/E2 are clear differentiated.

Acetone is one such solvent right? If I understand correctly, aprotic means that it has no O-H bonds (like water and all alcohols). Simple ketones generally don't have such bonds since the oxygen bonds to carbon only.


Offline Babcock_Hall

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Re: Major product of 2-iodopropane + sodium ethoxide
« Reply #16 on: November 26, 2020, 04:45:32 PM »
Yes, you are correct about acetone.  DMF and DMSO are two other polar, aprotic solvents.

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