Rather, you don't understand the essence of solubility.
Polar compounds (and such is adenosine) dissolve better in polar solvents (and such is water).
In Pharmacy (rather topically) DMSO is sometimes used (in which adenosine dissolves better).
And those are probably all options.
Thanks for the reply. I'm very aware of the basic principles of solubility.
I honestly don't understand why we're even discussing this.
I clearly stated that I'm looking for other vehicles that can possibly solubilize pure anhydrous adenosine.@rolnor
Got it immediately and proposed a potential solvent, i.e. methanol (which is exactly what I asked for).
But you simply keep repeating what I said in my original post.
Also, there are many proprietary solvents like TrichoSol, which clearly you aren't aware of because you think that DMSO is the end all be all.
TrichoSol doesn't work in my case and that's why I'm posting a question here.
To gather ideas for other such solvents, be it proprietary or not.
Most importantly, there's clinical data in which adenosine is dissolved at 0.75% and is applied topically on the scalp for the treatment of androgenic alopecia, however, the methods of preparation aren't specified.
They surely aren't applying DMSO or methanol to people's scalps.
This means that there are skin-safe solvents out there that can dissolve adenosine at a higher than 0.30% concentration (which is the highest concentration in water).
Thanks a lot for taking the time to reply, though. I genuinely appreciate your input!
P.S. I did contact the authors of the adenosine 0.75% studies and got no replies.