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Topic: GC-MS Calibration Curve Help  (Read 317 times)

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Offline targe

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GC-MS Calibration Curve Help
« on: November 30, 2024, 02:46:13 AM »
 I will be making a calibration curve on a GC-MS and need to get a sample down to 500, 200, 100, 50, and 20 PPB.  The sample has a specific gravity of 1.145 and will be in Ethyl Acetate. Does anyone know how to go about doing the math for this?

I know that in water you can put .001 mL of sample into 1000 mL of water to get 1 PPM, but I don't know how to go about getting it in ethyl acetate.

The units at the end end up being ng/mL

Offline Borek

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Re: GC-MS Calibration Curve Help
« Reply #1 on: November 30, 2024, 03:33:48 AM »
I know that in water you can put .001 mL of sample into 1000 mL of water to get 1 PPM, but I don't know how to go about getting it in ethyl acetate.

Hint: this is correct assuming density of both the sample and solution is 1 g/mL.

Which is already based on another assumption: that you use ppm (ppb) defined as mass/mass. This is the most common way of using ppx to denote concentration, but not the only one.

Compare https://www.chembuddy.com/concentration-ppm-ppb-ppt
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