Which statement is FALSE regarding flavoproteins?
A) They may contain either FMN or FAD.
B) The reduction potential of the flavin will depend on the amino acids in the polypeptide chain.
C) They will need at least two substrates in order to function as enzymes.
D) The are always integral membrane proteins.
E) Most flavoproteins in electron transport have a lower reduction potential than coenzyme Q.
Why B and C are correct?
For B, negatively charged amino acids in a protein could decrease the reduction potential of the flavin, and the other way round for positively charged ones, since negatively charged amino acids could 'share' or 'donate' some of their electrons to decrease the burden of extra reduction potential. Let me know if my thinking are right.
For C, I don't get why flavoprotein requires at least two substrate to function as an enzyme?