August 08, 2022, 04:15:45 AM
Forum Rules: Read This Before Posting


Topic: 6 Amino Penicillianic acid project  (Read 354 times)

0 Members and 1 Guest are viewing this topic.

Offline nickgamer49

  • Very New Member
  • *
  • Posts: 2
  • Mole Snacks: +0/-0
6 Amino Penicillianic acid project
« on: February 28, 2022, 07:48:30 AM »
Hey! I am new to research and I am trying a project on the condensation to form
phenylpenicillin
(https://pubchem.ncbi.nlm.nih.gov/compound/6-_Benzoylamino_penicillanic-acid)
from 6-APA
(https://pubchem.ncbi.nlm.nih.gov/compound/6-Aminopenicillanic-acid#section=Crystal-Structures).

 I essentially mix 6apa dissolved in basic aqueous solution and benzoyl chloride in propanone to make the product. Because our lab doesnt have any spectroscopes and such, I acidify the solution and separate it with ethyl ethanoate. I am getting really bad yield with this process and a lot is hard to control. Does anyone have a better method or even a different topic involving the chemistry of 6APA? Thanks so much!


Offline billnotgatez

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 4324
  • Mole Snacks: +221/-61
  • Gender: Male
Re: 6 Amino Penicillianic acid project
« Reply #1 on: February 28, 2022, 07:57:46 AM »
We only post a given question to the forum once
This is a forum rule
see the link at the top of every page
Quote
Forum Rules: Read This Before Posting

This Thread is locked
See Organic chemistry board

Sponsored Links