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Topic: S- vs. O-alkylation using sodium sulfinates  (Read 8611 times)

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Offline rolnor

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Re: S- vs. O-alkylation using sodium sulfinates
« Reply #45 on: April 01, 2023, 01:47:07 AM »
Yields in patents can be lower than 1% in some cases.

Offline Babcock_Hall

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Re: S- vs. O-alkylation using sodium sulfinates
« Reply #46 on: April 03, 2023, 08:24:51 AM »
When diisopropyl bromomethylphosphonate comes in, I will test it using sodium phenylsulfinate, because I have the product that I can use as a standard.  At some point, I will also test the corresponding diethyl toluenesulfonate.  I did this once before, and I had some product formation, but not quite as much as I had hoped for.

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