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SN2 attack rate change depending on substrate
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ElectroMaster88:
I need to figure out with which molecule out of these two (A or B), NaOH will react faster in a SN2 mechanism.
I've been told that "In general, for SN2 chemistry, nucleophiles may only attack an electrophilic chair when the leaving group is in an axial position", but when I draw the chair conformations, the position of the Br changes depending on if the chair is flipped or not.
I don't know what to do with it.
Babcock_Hall:
You wrote "the position of the Br changes..." Can you explain in detail what you mean? I have an idea, but I want to make sure that we are on the same page.
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