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Topic: Karl Fisher titration question  (Read 475 times)

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Offline Duongtrung30

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Karl Fisher titration question
« on: June 24, 2024, 09:32:10 PM »
I'm working for a pharmaceutical company. We use KF volumetric titratior
to determine water in raw materials and products. We are currently using the
Metter toledo t7 device and 2 solutions of combititran 5 (lodine, imidazole,
2-methylimidazole) and combiMethanol for this test. I have 2 questions as
follows:
1. Where is sulfur dioxide dissolved? (because the labels of the above two
solutions do not mention sulfur dioxide),
2. If using 2 different solvent bottles, is this one-component reagent or
two-component reagent and why?

Offline Hunter2

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Re: Karl Fisher titration question
« Reply #1 on: June 25, 2024, 12:51:56 AM »
The SO2 is dissolved in the same bottle, where the Iodine, Methanol and Imidazole is in.
SO2 reacts with I2 only when get wet.

Offline Duongtrung30

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Re: Karl Fisher titration question
« Reply #2 on: June 25, 2024, 09:37:23 AM »
I know that, but the labels of Combititran 5 and CombiMethanol do not list SO2

Offline Hunter2

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Re: Karl Fisher titration question
« Reply #3 on: June 25, 2024, 02:27:39 PM »
Refer to  MSDS or use your nose carefully. Also the iodine gives brown colour.

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