October 09, 2024, 10:03:22 AM
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Topic: Proline found on helix or sheets?  (Read 3203 times)

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negss

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Proline found on helix or sheets?
« on: August 05, 2024, 07:44:20 AM »
Where is Proline residue located? Would it be found on both helix and sheets or on helix only? and where on the structure would it be found?

Offline Babcock_Hall

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Re: Proline found on helix or sheets?
« Reply #1 on: August 05, 2024, 10:01:53 AM »
Can you explain what you have learned so far in a little more detail?  Proline at position n restricts the available phi/psi dihedral angles of the preceding (n-1) residue in the polypeptide chain.  This has important consequences for its preferred secondary structure.  It also lacks a hydrogen atom on nitrogen; therefore, proline residues cannot donate H-bonds.  Regular secondary structure such as the alpha helix and the beta sheet have a regular pattern of hydrogen bonding between the carbonyl oxygen of one residue (the acceptor) and the amide group of a different residue (the donor).
« Last Edit: August 05, 2024, 01:50:46 PM by Babcock_Hall »

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