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Topic: Affymetrix chips and Small molecule!  (Read 3833 times)

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stalvl

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Affymetrix chips and Small molecule!
« on: October 20, 2004, 09:09:29 PM »
Hi guys!
I am working on cancer project. I have made my small molecule which kills cancer cells and trying to figure out the mechanism of its action, i.e. its protein target. Besides affinity purification, I am thinking to perform a global gene expression analysis ,using Affy chips, after treatment of cancer cells with my compound. I know I gonna get thousands of data points. Did you ever try something like that? If you know change in  mRNA  expresion can you find out the target?

Thanks :angel_not:

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