[AhmedEzatAlzawalaty]

i know that B-sitosterol blocks absorption of Cholesterol and decreases the cholesterol levels in serum , is this related to forming complex or some thing that way.?

[Yggdrasil]

Fernandez ML, Vega-Lopez S.  Efficacy and safety of sitosterol in the management of blood cholesterol levels.  Cardiovasc Drug Rev. 2005 Spring;23(1):57-70.

According to the abstract of this article:  "It is well known that plant sterols compete with cholesterol for space within bile salt micelles in the intestinal lumen thereby reducing cholesterol absorption. The understanding of the function of plant sterols in impeding cholesterol absorption has been clarified with the discovery of the adenosine binding cassette transporters, ABCG5/8, involved in the regulation of sterol absorption and secretion into the enterocyte and hepatocyte. Compared to cholesterol and other sterols, sitosterol is preferentially pumped out to the intestinal lumen by the ABCG5/8 transporters. This selective binding of sitosterol to the transporters ultimately results in significant lowering of plasma cholesterol."

[AhmedEzatAlzawalaty]

thank u thats helpful