March 05, 2024, 09:08:42 AM
Forum Rules: Read This Before Posting


Topic: can knoevenagel reaction catalyzed by lewis acid catalyst??  (Read 4415 times)

0 Members and 1 Guest are viewing this topic.

Offline zai85

  • Very New Member
  • *
  • Posts: 2
  • Mole Snacks: +0/-0
hello..
can knoevenagel reaction catalyzed by lewis acid catalyst??

can anybody help me on this question and hope some of us can give me an explanation on this topic.

as far as i know, knoevenagel reaction is only catalyzed by base catalyst but i heard some fact that this reaction can also being catalyzed by lewis acid catalyst..
but, i still got no information and further reference on this..

hope to get some information...
thank you so much!


Offline sjb

  • Global Moderator
  • Sr. Member
  • ***
  • Posts: 3653
  • Mole Snacks: +222/-42
  • Gender: Male
Re: can knoevenagel reaction catalyzed by lewis acid catalyst??
« Reply #1 on: July 12, 2007, 05:09:24 AM »
It may not be quite what you're after, but for instance http://dx.doi.org/10.1021/ol027081j, specifically references 5 and 12 suggest Lewis acid promotion of Knoevenagels.

S

Offline AWK

  • Retired Staff
  • Sr. Member
  • *
  • Posts: 7981
  • Mole Snacks: +555/-93
  • Gender: Male
Re: can knoevenagel reaction catalyzed by lewis acid catalyst??
« Reply #2 on: July 12, 2007, 07:15:05 AM »
Chem. Commun., 2007, 2284–2286
AWK

Sponsored Links