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Topic: Solvents and Solubility  (Read 5337 times)

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Offline k42490

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Solvents and Solubility
« on: December 22, 2007, 09:00:05 PM »
My question is: In flushing and cleaning columns used in liquid chromatography to remove absorbed contaminants, a series of solvents is used. Hexane C6H14, chloroform CHCl3, methanol CH3OH, and water are passed through the column in that order. Rationalize the order in terms of intermolecular forces and the mutual solubility of the solvents.

I don't know where to start.

Offline enahs

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Re: Solvents and Solubility
« Reply #1 on: December 22, 2007, 09:26:45 PM »
Start with: As the compound is changed, they become more and more polar. Why? What does this do?

Offline IITian

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Re: Solvents and Solubility
« Reply #2 on: December 23, 2007, 07:06:50 AM »
you can see that the solvents change from being apolar hexane to being a polar protic solvent (water)

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