Hi guys, I think I am hit with another problem. This time I need to prepare 10mL of 1000ppm(ug/mL) of Penicillin G. I have with me Sigma Penicillin G Sodium Salt, MF:C16H17N2NaO4S , MW: 356.37, Moisture Content:0.13% and potency of 1658 units Penicillin-G Base per mg.
As you can see, the potency given is in units per mg. I read online that in international Standard, 1 mg of pure Penicillin G Sodium has 1666 units Penicillin G per mg.
Singe I need 10mg of Penicillin G, to dissolve in 10mL buffer to yeild 1000ppm, I need 1666units * 10 = 16660units of penicillin G.
So amount to weigh = 16660 / 1658