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Topic: e- spray vs maldi-tof  (Read 3795 times)

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Offline glycogrl07

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e- spray vs maldi-tof
« on: April 12, 2008, 04:30:36 PM »
I am trying to determine the (dis)advantages of electron spray and maldi-tof.  I can not find too much online info about either.  I really just want to know how electron spray works.  I understand maldi/mass spec.  Any help is appreciated.

Thanks
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Offline Arkcon

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Re: e- spray vs maldi-tof
« Reply #1 on: April 12, 2008, 04:38:39 PM »
Making the concept as simple as possible -- electrospray is a little more aggressive compared to APCI, but MALDI is even more gentle.  It all depends on whether you want source level fragmentation, or not
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Offline chiralic

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Re: e- spray vs maldi-tof
« Reply #2 on: April 13, 2008, 01:07:03 PM »
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Offline Mitch

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Re: e- spray vs maldi-tof
« Reply #3 on: April 13, 2008, 01:12:35 PM »
An other tidbit for electrospray, in order for it to work the analyte needs to be ionizable in solution.
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