April 23, 2024, 08:41:42 AM
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Topic: Rotovap vs. Heating on hot plate  (Read 4510 times)

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Offline whawhaxd

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Rotovap vs. Heating on hot plate
« on: April 11, 2009, 01:16:20 AM »
Rotovap in my lab does't work anymore :(
My solvent for one reaction is water and for another reaction is ethyl acetate. For either of the two, is anything gonna be different if I just boil it off by heating in an oil-bath at like 110 degress?

Any other good and easy ways to remove those?

Thank you!!!!!!!!!!

Offline macman104

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Re: Rotovap vs. Heating on hot plate
« Reply #1 on: April 11, 2009, 01:40:36 AM »
The main purpose of the rotovap, is that some compounds may decompose at high temperatures.  If your compounds will not be wrecked by the high temperatures, then you shouldn't worry.

Offline lutesium

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Re: Rotovap vs. Heating on hot plate
« Reply #2 on: April 11, 2009, 04:26:16 AM »
And faster evaporation due to higher surface area created by stirring and also with vacuum.


Lutesium...

Offline whawhaxd

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Re: Rotovap vs. Heating on hot plate
« Reply #3 on: April 11, 2009, 12:38:58 PM »
So, basically there is no difference unless high temperature would damage my product, right?

Offline lutesium

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Re: Rotovap vs. Heating on hot plate
« Reply #4 on: April 12, 2009, 06:19:53 AM »
And the loss of reaction solvent. For water it doesn't matter but for EtOAc the loss of reaction solvent matters so why don't you simply distill off?


Lutesium...

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