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Topic: Enzimatic Reaction limited by Diffusion rate  (Read 3039 times)

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Offline Sosi

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Enzimatic Reaction limited by Diffusion rate
« on: January 25, 2010, 09:40:10 AM »
Hello everyone!

I have a "simple" question I think: considering the following enzimatic reaction


Trxo + NADPH  :rarrow: Trxr + NADP+

I am considering this reaction to have an excess of NADPH. And someone told me to consider that the reaction between the enzime (a reductase) and Trxr to be a diffusion limited process, with a rate constant of 109 M-1 s-1.

I know that the value for the rate constant is approximately 10-9, and I know that this value is just a bare approximation. His assumption to get this value was just that this must be a reaction with a relatively low reaction rate. However, I would like to know how does this correlate with the diffusion rate? I.e. does the diffusion rate have any particular effect in this case?

If you need any other input on the reaction or the metabolic system, please let me know.

Thanks for all the help

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