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Topic: Reduction of 3-Nitroacetophenone  (Read 9292 times)

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Offline kcchan128

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Reduction of 3-Nitroacetophenone
« on: October 17, 2010, 09:21:14 PM »
This is a chemoselective reduction as there are 2 possible functional groups that will be reduce depending on which reducing agent will be used.
Sn/HCl was used as the reducing agent in the experiment. I tried writting out the balanced equation for the reduction.
how can I calculate for the number of equivalent of tin (relative to 3-nitroacetophoenone)?
Is it depends on the electrons or just the stoichiometric ratio of both the starting materials (1:1)?




Offline majorjp

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Re: Reduction of 3-Nitroacetophenone
« Reply #1 on: October 21, 2010, 05:24:46 AM »
It does depend on the electrons, which in this case will require 3e- for the full reduction of the nitro group and 1e- for the reduction of the ketone. However it should be noted that for the reduction of the ketone group ethanoic acid in place of HCl is the most common solvent for that reduction.

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