[shrikantvarma]

is it possible to perform witting reaction of alpha halo ketone ( in my case i using alpha bromomethyl isopropyl ketone) i am getting some unknown products pls explain??

[discodermolide]

is it possible to perform witting reaction of alpha halo ketone ( in my case i using alpha bromomethyl isopropyl ketone) i am getting some unknown products pls explain??

What is your Wittig reagent? You may get attack at the carbonyl followed by epoxide formation similar to sulphur ylids

[shrikantvarma]

Thanks for reply.
i used methyledene triphenyl phosphorane as witting reagent?? can i brominate after witting reaction ?? will it work as i think alkene formation there might be problem in bromination??

[discodermolide]

Thanks for reply.
i used methyledene triphenyl phosphorane as witting reagent?? can i brominate after witting reaction ?? will it work as i think alkene formation there might be problem in bromination??

If you get the olefin you can brominate it under normal conditions.

[shrikantvarma]

thanks,
will bromination will not go to alkene which will be the ideal condition???

[discodermolide]

thanks,
will bromination will not go to alkene which will be the ideal condition???

I said above, if you get the olefin (alkene) it will brominate