April 27, 2024, 07:56:03 PM
Forum Rules: Read This Before Posting


« previous next »
Pages: [1]   Go Down

Topic: conversion help  (Read 3308 times)

0 Members and 1 Guest are viewing this topic.

Offline GSR

  • Regular Member
  • ***
  • Posts: 48
  • Mole Snacks: +9/-1
  • Gender: Male
  • Have Courage and Follow Your Own Path!
conversion help
« on: September 10, 2005, 08:23:12 AM »
hi,

I want to convert p-nitrobenzyl bromide to p-chlorobenzyl bromide any suggesions plz.

regards
GSR
Logged

Offline HP

  • Chemist
  • Full Member
  • *
  • Posts: 350
  • Mole Snacks: +33/-5
  • Gender: Male
Re:conversion help
« Reply #1 on: September 10, 2005, 11:01:39 AM »
Hi
I suggest you this following synthesis:
First step standart reduction of NO2 group with Zn/HCl p-nitrobenzyl bromide to p-aminophenyl bromide and next step diazotation of this with NaNO2/HCl to its diazonium cloride salt next Zandmayer synthesis with catalitic amount of CuCl with heatin to obtain the desired product  :)
Logged
xpp
Pages: [1]   Go Up
« previous next »
Sponsored Links