April 28, 2024, 10:37:39 PM
Forum Rules: Read This Before Posting


Topic: Pink or Red Coloration after addition of benzophenone in synthesis of triphenylm  (Read 3715 times)

0 Members and 1 Guest are viewing this topic.

Offline berkeleynoob

  • Very New Member
  • *
  • Posts: 1
  • Mole Snacks: +0/-0
Hi,
This question has to do with synthesis of triphenylmethanol. Immediately after the rapid addition of a benzophenone solution (composed of benzophenone and anhydrous ether) to a phenylmagnesium bromide solution (containing , a noticeably bright pink coloration was observed. What is the cause for this pink coloration? A detailed explanation would be appreciated.

Offline MOTOBALL

  • Full Member
  • ****
  • Posts: 371
  • Mole Snacks: +50/-5
Some years ago, I used to use a procedure for N,O-permethylation of peptides.  This involved warming DMSO with NaH to form a strong base.  Completion of the reaction was assessed by spotting a few uL of the solution onto a few crystals of triphenylmethane.  A bright red coloration indicated the successful formation of the base, which abstracted a H radical to leave the red Trityl radical.

You may have a similar reaction here.

Sponsored Links